Annotation Overview for fig|393595.12.peg.2061 in Alcanivorax borkumensis SK2:
FIG134348: essential endopeptidase

current assignment	FIG134348: essential endopeptidase
taxonomy id	393595	contig	393595.12:NC_008260 (3,120,144bp)
internal links	genome browser | feature evidence | sequence	ACH Annotation Clearinghouse (ACH) The Annotation Clearinghouse offers a mapping of genes which are identical in sequence except for the start region (due to differences in start calling). [?]	show essentially identical genes
annotation history		run tool	Psi-BlastTMpredTMHMMGram negative PSORTGram negative SignalPGram positive PSORTGram positive SignalPLipoPInterProScanRadarPPSearchGram negative CELLOGram positive CELLOProDomPDB
FigFam	FIG134348
data base cross references (dbxref)	UniProt: Q0VMU1 UniProt: GCP_ALCBS NCBI: 122959346 NCBI: 110648031 RefSeq: YP_693779.1 CMR: NTL01AB2059 NCBI: 110834920

Annotation History (history of similar genes)

Date	Annotator	Annotation
1/8/2007	rapid_propogation	Set function to proteolysis and peptidolysis; Main role: Protein fate; Subrole: Degradation of proteins, peptides,and glycopeptides. from original annotations
1/8/2007	rapid_propogation	Set function to O-sialoglycoprotein endopeptidase based on FIGfams
4/13/2007	gjo	Set FIG function to Endopeptidase essential in most Bacteria (E. coli YgjD/B. subtilis YdiE)
4/13/2007	gjo	Characterized as "O-sialoglycoprotein endopeptidase (EC 3.4.24.57)" in Pasteurella haemolytica serotype A1
2/2/2009	DanielaB	Set FIG function to FIG134348: essential endopeptidase
2/2/2009	DanielaB	Role changed from 'Endopeptidase essential in most Bacteria (E. coli YgjD/B. subtilis YdiE)' to 'FIG134348: essential endopeptidase'
2/2/2009	DanielaB	Master function set by DanielaB at 1233579338 FIG134348: essential endopeptidase

We have assigned the function "FIG134348: essential endopeptidase" to the encoded protein. The protein occurs in 3 subsystems: "Bacterial RNA-metabolizing Zn-dependent hydrolases", "Conserved gene cluster associated with Met-tRNA formyltransferase", and "YgjD and YeaZ". In "Bacterial RNA-metabolizing Zn-dependent hydrolases", it appears to play a functional role that we have not associated with any other gene. In "Conserved gene cluster associated with Met-tRNA formyltransferase", it appears to play a functional role that we have not associated with any other gene. In "YgjD and YeaZ", it appears to play a functional role that we have not associated with any other gene. The function of genes having the same functional roles have been described in Escherichia coli (9743119) and Bacillus subtilis (15044829). These are homologous proteins which implement the same function.

The chromosomal region of the focus gene (top) is compared with four similar organisms. The graphic is centered on the focus gene, which is red and numbered 1. Sets of genes with similar sequence are grouped with the same number and color. Genes whose relative position is conserved in at least four other species are functionally coupled and share gray background boxes. The size of the region and the number of genomes may be reset. Click on any arrow in the display to refocus the comparison on that gene. The focus gene always points to the right, even if it is located on the minus strand.